How can I treat my cats upper respiratory infection at home

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Sick cat
Sick Cat

Upper respiratory infections are very common in cats, especially kittens and shelter cats. These infections usually respond well to treatment, though some cats can become quite ill, with severe cases occasionally becoming pneumonia.

What Is an Upper Respiratory Infection?

The term upper respiratory infection actually describes a complex variety of diseases that can occur alone or in combination. Generally, all of these diseases produce a similar set of symptoms that mainly affect the upper respiratory tract (i.e. mainly the nose and throat).


The symptoms of upper respiratory infections in cats can vary in severity, but typically include any or all of the following:

brown tabby cat on tree trunk
brown tabby cat on tree trunk
  • Fever
  • Nasal discharge
  • Sneezing
  • Runny eyes
  • Reddened eyes (conjunctivitis)
  • Squinting
  • Cough
  • Hoarse voice
  • Sores in the mouth and/or nose
  • Drooling
  • Gagging
  • Rapid breathing
  • Loss of appetite
  • Lethargy


There are numerous organisms that cause upper respiratory infections in cats, but the common culprits are:

  • Feline herpesvirus 1, also called rhinotracheitis virus
  • Feline calicivirus of which there are several strains
  • Chlamydophila felis, a bacteria
  • Mycoplasma spp, a type of bacteria

The majority of cases are due to viral infections with herpesvirus and/or calicivirus.

Risk Factors

Kittens and shelter cat's are at high risk. Upper respiratory infections most common in cats who regularly have contact with other cats where cats are housed together in places such as shelters.

Unvaccinated cats, cats that are under stress, and cats that are immunosuppressed because of conditions such as feline leukemia virus (FeLV) or feline immunodeficiency virus (FIV) are also at greater risk. Flat-faced cats, such as Persians, seem particularly susceptible to upper respiratory infections.

grayscale photography of cat
grayscale photography of cat

Upper respiratory infections are spread via the discharge from the nose and eyes, either by direct contact with infected cats, aerosol contamination or by contact with objects like dishes or bedding that have been contaminated with secretions from infected cats.


A diagnosis of upper respiratory infection can often be made on the basis of history and symptoms. Further diagnostic tests can be done on the secretions to identify the organisms causing disease.


For most cats, treatment is aimed at managing the symptoms. Though most cases are caused by viruses, antibiotics may be prescribed to fight bacterial infections that often occur secondary to viral infections. An eye ointment may be prescribed as well, and medications to help control the nasal congestion and discharge may also be prescribed.

brown, white, and black maine coon cat macro photography
brown, white, and black maine coon cat macro photography

Many upper respiratory infections your vet will provide treatments for you to do at home, but in cases where cats won't eat or drink or have serious breathing difficulties, hospitalization may be required. Intravenous fluids may be given to prevent dehydration and oxygen therapy can be used if necessary.

Most cases clear up within a week to 10 days, although sometimes upper respiratory infections will hang on for a few weeks. For cases that do not respond to the usual supportive treatment, antiviral medications can be tried. Cats that suffer prolonged or repeated bouts of respiratory infections should be checked for FeLV and FIV even if the pet tested negative previously.

Once the symptoms have resolved, cats infected with herpesvirus continue to carry the virus forever, and can have flare ups from time to time. With herpesvirus, the infection is usually only active after times of stress and may have a relapse (show symptoms again).

tabby cat lying on the floor
tabby cat lying on the floor


Vaccines against both herpesvirus and calicivirus are part of the routine vaccination protocol that will be recommended by veterinarians. They are most often given by injection and your vet can discuss which vaccine to use and an appropriate vaccination schedule for your cat. In young kittens, the vaccines are not fully protective until the full series of vaccines are given.

Minimizing stress, as well as preventing contact with infected cats, can also reduce the incidence of upper respiratory infections.

Home Care

Cats should be kept quiet and comfortable during the course of an upper respiratory infection. Carefully wipe away discharge from the eyes and nose, and administer all medications as prescribed by your vet. A humidifier can often help with managing the congestion.

brown tabby cat on white snow
brown tabby cat on white snow
tuxedo cat on white textile
tuxedo cat on white textile

Because cats might lose their sense of smell or have painful sores in their mouths, their appetites may suffer. You can try feeding their favorite, extra-tasty canned food, or even a special veterinary diet that provides extra nutritional support if your cat's appetite is diminished. However, if your cat won't eat or drink at all, consult your vet.

In multi-cat households, speak to your vet about any precautions you should take to minimize the risk to other susceptible cats in the home, such as isolating sick cats or disinfecting food bowls and bedding.